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Merck

TLR4

toll-like receptor 4

Sinonimi:
ARMD10, CD284, TLR-4, TOLL
Specie:
ID UniProtKB:
ID gene:
  • Human(7099) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(21898) toll-like receptor 4
  • Rat(29260) toll-like receptor 4
  • naked mole-rat(101715916) toll-like receptor 4
  • dog(403417) toll-like receptor 4
  • cow(281536) toll-like receptor 4
  • Horse(100066890) toll-like receptor 4
  • Domestic Rabbit(100009497) toll-like receptor 4
  • sheep(554263) toll-like receptor 4
  • Goat(100860955) toll-like receptor 4
  • domestic guinea pig(100724803) toll-like receptor 4
  • domestic cat(493698) toll-like receptor 4
  • chicken(417241) toll-like receptor 4

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human TLR-4 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-TLR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-TLR4 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-TLR4 antibody produced in mouse, clone 3B6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-TLR4 Antibody, clone 2N20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey
Applicazione
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human TLR4,
Specie
human