SMAD4
SMAD family member 4
Sinonimi:
DPC4, JIP, MADH4, MYHRS
Specie:
Human SMAD4 (4089), Mouse Smad4 (17128), Rat Smad4 (50554), dog SMAD4 (476196), domestic cat SMAD4 (101093650), Zebrafish smad4 (30640), domestic guinea pig Smad4 (100717853), naked mole-rat Smad4 (101703764), sheep SMAD4 (443171), cow SMAD4 (540248) ...Più
ID UniProtKB:
ID gene:
- Human(4089) Summary: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]
- Mouse(17128) SMAD family member 4
- Rat(50554) SMAD family member 4
- dog(476196) SMAD family member 4
- domestic cat(101093650) SMAD family member 4
- Zebrafish(30640) MAD homolog 4 (Drosophila)
- domestic guinea pig(100717853) SMAD family member 4
- naked mole-rat(101703764) SMAD family member 4
- sheep(443171) SMAD family member 4
- cow(540248) SMAD family member 4
- Horse(100033846) SMAD family member 4
- Goat(100861019) SMAD family member 4
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ELISA
N° Catalogo
Descrizione
Specie
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-SMAD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SMAD4 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM277, purified immunoglobulin,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Monoclonal Anti-SMAD4 antibody produced in mouse, clone 4G1C6, ascites fluid,
Reattività con
human
Applicazione
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Anti-Smad4/DPC4 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
chimpanzee, human, mouse, rat
Applicazione
immunocytochemistry
western blot
western blot
Anti-SMAD4 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, sheep
Applicazione
immunohistochemistry
western blot
western blot
Proteins
N° Catalogo
Descrizione
Specie
SMAD4, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human