RB1
retinoblastoma 1
Sinonimi:
OSRC, RB, p105-Rb, pRb, pp110
Specie:
Human RB1 (5925), Mouse Rb1 (19645), Rat Rb1 (24708), chicken RB1 (386582), Zebrafish rb1 (777733), domestic cat RB1 (101101356), dog RB1 (476915), cow RB1 (534712), Horse RB1 (100057080), sheep RB1 (100144755) ...Più
ID UniProtKB:
ID gene:
- Human(5925) Summary: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
- Mouse(19645) retinoblastoma 1
- Rat(24708) retinoblastoma 1
- chicken(386582) retinoblastoma 1
- Zebrafish(777733) retinoblastoma 1
- domestic cat(101101356) retinoblastoma 1
- dog(476915) retinoblastoma 1
- cow(534712) retinoblastoma 1
- Horse(100057080) retinoblastoma 1
- sheep(100144755) retinoblastoma 1
- Domestic Rabbit(100357431) retinoblastoma 1
- domestic guinea pig(100716297) retinoblastoma 1
- naked mole-rat(101703701) retinoblastoma 1
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Retinoblastoma, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-phospho-Retinoblastoma (pSer608) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
western blot
Anti-Phospho-Rb-S807/811 antibody produced in rabbit, ,
Reattività con
human
Applicazione
western blot
Anti-RB antibody produced in rabbit, ,
Reattività con
human, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-p-Rb-Ser807/811 Antibody, clone 3J7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, rat
Applicazione
flow cytometry
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
Kits
N° Catalogo
Descrizione
Specie
CpG WIZ™ RB1 - Methylation specific PCR assay, MSP, performed using the CpGenome DNA Modification Kit & the CpG WIZ RB1 Amplification Kit, permits sensitive detection of altered DNA.,
Specie
human
Proteins
N° Catalogo
Descrizione
Specie
Retinoblastoma Protein (aa 773-928), Recombinant fusion protein containing the C-terminal fragment (residues 773-928) of human retinoblastoma protein (Rb) with an N-terminal His6-tag, expressed in E. coli.,
Specie
human
Retinoblastoma protein human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Specie
human