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Merck

RASAL1

RAS protein activator like 1 (GAP1 like)

Sinonimi:
RASAL
Specie:
ID UniProtKB:
ID gene:
  • Human(8437) Summary: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010]
  • Mouse(19415) RAS protein activator like 1 (GAP1 like)
  • Rat(360814) RAS protein activator like 1 (GAP1 like)
  • dog(486277) RAS protein activator like 1 (GAP1 like)
  • chicken(771057) RAS protein activator like 1 (GAP1 like)
  • naked mole-rat(101697586) RAS protein activator like 1 (GAP1 like)
  • domestic guinea pig(100717596) RAS protein activator like 1 (GAP1 like)
  • Domestic Rabbit(100341044) RAS protein activator like 1 (GAP1 like)
  • cow(512872) RAS protein activator like 1 (GAP1 like)
  • sheep(101109393) RAS protein activator like 1 (GAP1 like)
  • domestic cat(101088621) RAS protein activator like 1 (GAP1 like)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-RASAL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Rasal1,
Specie
mouse
MISSION® esiRNA, targeting human RASAL1,
Specie
human