PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
Sinonimi:
AMPK, AMPK2, AMPKa2, PRKAA
Specie:
Human PRKAA2 (5563), Mouse Prkaa2 (108079), Rat Prkaa2 (78975), sheep PRKAA2 (100127210), domestic guinea pig Prkaa2 (100713170), naked mole-rat Prkaa2 (101698482), domestic cat PRKAA2 (101096000), dog PRKAA2 (489571), cow PRKAA2 (538954), Horse PRKAA2 (100034159) ...Più
ID UniProtKB:
ID gene:
- Human(5563) Summary: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
- Mouse(108079) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Rat(78975) protein kinase, AMP-activated, alpha 2 catalytic subunit
- sheep(100127210) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic guinea pig(100713170) protein kinase, AMP-activated, alpha 2 catalytic subunit
- naked mole-rat(101698482) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic cat(101096000) protein kinase, AMP-activated, alpha 2 catalytic subunit
- dog(489571) protein kinase, AMP-activated, alpha 2 catalytic subunit
- cow(538954) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Horse(100034159) protein kinase, AMP-activated, alpha 2 catalytic subunit
- chicken(429110) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Zebrafish(572074) protein kinase, AMP-activated, alpha 2 catalytic subunit
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-phos-AMPKα (Thr172) Antibody, clone 5J23 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse
Applicazione
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
immunohistochemistry
inhibition assay
western blot
Anticorpo anti-AMPK alfa 1/2, clone 34.2, clone 34.2, from mouse,
Reattività con
drosophila, human, mouse, rat
Applicazione
western blot
Anti-AMPK α2 Antibody, Upstate®, from rabbit,
Reattività con
human, rat
Applicazione
western blot
Anti-PRKAA2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, canine, human, mouse, rabbit, rat
Applicazione
ELISA
western blot
western blot
Anti-PRKAA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
N° Catalogo
Descrizione
Specie
AMPK (α2, β1, γ1) Protein, active, 10 µg, Active, recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
Specie
human
AMPK (α2/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
AMPK (α2/β2/γ2), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
esiRNA
N° Catalogo
Descrizione
Specie