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Merck

PNPLA6

patatin-like phospholipase domain containing 6

Sinonimi:
NTE, NTEMND, SPG39, iPLA2delta, sws
Specie:
ID UniProtKB:
ID gene:
  • Human(10908) Summary: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(50767) patatin-like phospholipase domain containing 6
  • Rat(360753) patatin-like phospholipase domain containing 6
  • Horse(100060640) patatin-like phospholipase domain containing 6
  • Zebrafish(386860) patatin-like phospholipase domain containing 6
  • chicken(425396) patatin-like phospholipase domain containing 6
  • domestic guinea pig(100714197) patatin-like phospholipase domain containing 6
  • naked mole-rat(101724286) patatin-like phospholipase domain containing 6
  • cow(767822) patatin-like phospholipase domain containing 6
  • sheep(101123119) patatin-like phospholipase domain containing 6
  • dog(484993) patatin-like phospholipase domain containing 6
  • domestic cat(101097705) patatin-like phospholipase domain containing 6

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-PNPLA6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-PNPLA6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
Monoclonal Anti-NTE, (C-terminal) antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Pnpla6,
Specie
mouse
MISSION® esiRNA, targeting human PNPLA6,
Specie
human