PLCG1
phospholipase C, gamma 1
Sinonimi:
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Specie:
Human PLCG1 (5335), Mouse Plcg1 (18803), Rat Plcg1 (25738), naked mole-rat Plcg1 (101705192), chicken PLCG1 (419175), dog PLCG1 (485874), Zebrafish plcg1 (373867), domestic cat PLCG1 (101092925), cow PLCG1 (281987), domestic guinea pig Plcg1 (100716986)
ID UniProtKB:
ID gene:
- Human(5335) Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18803) phospholipase C, gamma 1
- Rat(25738) phospholipase C, gamma 1
- naked mole-rat(101705192) phospholipase C, gamma 1
- chicken(419175) phospholipase C, gamma 1
- dog(485874) phospholipase C, gamma 1
- Zebrafish(373867) phospholipase C, gamma 1
- domestic cat(101092925) phospholipase C, gamma 1
- cow(281987) phospholipase C, gamma 1
- domestic guinea pig(100716986) phospholipase C, gamma 1
- sheep(101103341) phospholipase C, gamma 1
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-PLCG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-PLCγ-1 Antibody, Upstate®, from mouse,
Reattività con
bovine, human, mouse, rabbit, rat
Applicazione
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Monoclonal Anti-PLCG1 antibody produced in mouse, clone 2A2, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-PLCG1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
immunofluorescence