MAP3K7
mitogen-activated protein kinase kinase kinase 7
Sinonimi:
MEKK7, TAK1, TGF1a
Specie:
Human MAP3K7 (6885), Mouse Map3k7 (26409), Rat Map3k7 (313121), Zebrafish map3k7 (553788), Horse MAP3K7 (100065841), Domestic Rabbit MAP3K7 (100343571), dog MAP3K7 (474996), chicken MAP3K7 (421808), domestic guinea pig Map3k7 (100718100), naked mole-rat Map3k7 (101718269) ...Più
ID UniProtKB:
ID gene:
- Human(6885) Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(26409) mitogen-activated protein kinase kinase kinase 7
- Rat(313121) mitogen activated protein kinase kinase kinase 7
- Zebrafish(553788) mitogen activated protein kinase kinase kinase 7
- Horse(100065841) mitogen-activated protein kinase kinase kinase 7
- Domestic Rabbit(100343571) mitogen-activated protein kinase kinase kinase 7
- dog(474996) mitogen-activated protein kinase kinase kinase 7
- chicken(421808) mitogen-activated protein kinase kinase kinase 7
- domestic guinea pig(100718100) mitogen-activated protein kinase kinase kinase 7
- naked mole-rat(101718269) mitogen-activated protein kinase kinase kinase 7
- domestic cat(101095899) mitogen-activated protein kinase kinase kinase 7
- cow(529146) mitogen-activated protein kinase kinase kinase 7
- sheep(100294587) mitogen-activated protein kinase kinase kinase 7
- sheep(101108056) mitogen-activated protein kinase kinase kinase 7
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-phospho-TAK1 (Ser412) Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse
Applicazione
western blot
Anti-TAK1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
western blot
Anti-phospho-TAK1 (pThr184) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
western blot
Anti-MAP3K7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
Anti-MAP3K7 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Numero di prodotto
Descrizione
Specie
TAK1-TAB1 fusion Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human TAK1 amino acids 1-303, fused to human TAB1 amino acids 437-end, for use in Kinase Assays.,
Specie
human
TAK1-TAB1 (1-303), (437-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human