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Merck

KREMEN2

kringle containing transmembrane protein 2

Sinonimi:
KRM2
Specie:
ID UniProtKB:
ID gene:
  • Human(79412) Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(73016) kringle containing transmembrane protein 2
  • Rat(287102) kringle containing transmembrane protein 2
  • naked mole-rat(101720049) kringle containing transmembrane protein 2
  • domestic cat(101098677) kringle containing transmembrane protein 2
  • sheep(101119273) kringle containing transmembrane protein 2
  • domestic guinea pig(100734476) kringle containing transmembrane protein 2
  • cow(618527) kringle containing transmembrane protein 2
  • dog(610753) kringle containing transmembrane protein 2

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ELISA

N° Catalogo
Descrizione
Specie
Human Kremen-2 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-KREMEN2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-KREMEN2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ELISA
immunocytochemistry

western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Kremen2,
Specie
mouse