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Merck

IL10RA

interleukin 10 receptor, alpha

Sinonimi:
CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
Specie:
ID UniProtKB:
ID gene:
  • Human(3587) Summary: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(16154) interleukin 10 receptor, alpha
  • Rat(117539) interleukin 10 receptor, alpha
  • sheep(101120946) interleukin 10 receptor, alpha
  • domestic guinea pig(100727507) interleukin 10 receptor, alpha
  • dog(610823) interleukin 10 receptor, alpha
  • naked mole-rat(101706532) interleukin 10 receptor, alpha
  • Zebrafish(777651) interleukin 10 receptor, alpha
  • domestic cat(101087601) interleukin 10 receptor, alpha
  • cow(513478) interleukin 10 receptor, alpha
  • chicken(419771) interleukin 10 receptor, alpha

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-IL-10R α antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot
Anti-IL10RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
Anti-phospho-IL10RA (pSer319/323) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
western blot
Anti-IL10RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
western blot