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Merck

GPX4

glutathione peroxidase 4

Sinonimi:
GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx
Specie:
ID UniProtKB:
ID gene:
  • Human(2879) Summary: Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008]
  • Mouse(625249) glutathione peroxidase 4
  • Rat(29328) glutathione peroxidase 4
  • domestic guinea pig(100730119) glutathione peroxidase 4
  • naked mole-rat(101708875) glutathione peroxidase 4
  • Thale Cress(819427) glutathione peroxidase 4
  • chicken(374056) glutathione peroxidase 4
  • domestic cat(101095956) glutathione peroxidase 4
  • cow(286809) glutathione peroxidase 4
  • Goat(100860867) glutathione peroxidase 4
  • sheep(101113149) glutathione peroxidase 4

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-GPX4 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-Glutathione Peroxidase 4 Antibody, clone Mab63-1, clone Mab63-1, from mouse, purified by affinity chromatography,
Reattività con
human, mouse
Applicazione
dot blot
electron microscopy

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-GPx4 Antibody, clone 1B4, clone 1B4, from rat,
Reattività con
mouse
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-GPX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
Anti-GPX4, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human GPX4,
Specie
human