GCK
glucokinase (hexokinase 4)
Sinonimi:
FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, LGLK, MODY2
Specie:
Human GCK (2645), Mouse Gck (103988), Rat Gck (24385), Zebrafish gck (751668), chicken GCK (430370), domestic cat GCK (100037406), dog GCK (606490), sheep GCK (101117412), cow GCK (616576), Horse GCK (100051836) ...Più
ID UniProtKB:
ID gene:
- Human(2645) Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009]
- Mouse(103988) glucokinase
- Rat(24385) glucokinase
- Zebrafish(751668) glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
- chicken(430370) glucokinase (hexokinase 4)
- domestic cat(100037406) glucokinase (hexokinase 4)
- dog(606490) glucokinase (hexokinase 4)
- sheep(101117412) glucokinase (hexokinase 4)
- cow(616576) glucokinase (hexokinase 4)
- Horse(100051836) glucokinase (hexokinase 4)
- naked mole-rat(101721664) glucokinase (hexokinase 4)
- domestic guinea pig(100717630) glucokinase (hexokinase 4)
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-GCK antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Glucokinase/GCK Antibody, clone 9G1.2, clone 9G1.2, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-Glucokinase (GCK) Antibody, clone 4K9D5, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-GCK, (C-terminal) antibody produced in mouse, clone 1G10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anti-GCK antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot
western blot
esiRNA
N° Catalogo
Descrizione
Specie