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Merck

EP300

E1A binding protein p300

Sinonimi:
KAT3B, RSTS2, p300
Specie:
ID UniProtKB:
ID gene:
  • Human(2033) Summary: This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
  • Mouse(328572) E1A binding protein p300
  • Rat(170915) E1A binding protein p300
  • dog(100684945) E1A binding protein p300
  • domestic guinea pig(100734820) E1A binding protein p300
  • chicken(418000) E1A binding protein p300
  • domestic cat(101088344) E1A binding protein p300
  • naked mole-rat(101711512) E1A binding protein p300
  • Horse(100055626) E1A binding protein p300
  • sheep(101110136) E1A binding protein p300

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-p300 CT Antibody, clone RW128, clone RW128, Upstate®, from mouse,
Reattività con
human, mouse, rat
Applicazione
ChIP
immunoprecipitation (IP)

western blot
Anti-EP300 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-EP300 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-phospho-p300 (pSer89) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
Monoclonal Anti-EP300 antibody produced in mouse, clone 1B1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

N° Catalogo
Descrizione
Specie
p300 (C1135-2414) human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Specie
human
p300, HAT Domain, Recombinant GST-fusion protein corresponding to amino acids 1066-1707 of human p300.,
Specie
human
P300 (1283-1673), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ep300,
Specie
mouse
MISSION® esiRNA, targeting human EP300,
Specie
human