CTSC
cathepsin C
Sinonimi:
CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS
Specie:
Human CTSC (1075), Mouse Ctsc (13032), Rat Ctsc (25423), domestic guinea pig Ctsc (100714387), naked mole-rat Ctsc (101697606), dog CTSC (403458), domestic cat CTSC (101092140), sheep CTSC (101112686), Zebrafish ctsc (368704), chicken CTSC (419014)
ID UniProtKB:
ID gene:
- Human(1075) Summary: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13032) cathepsin C
- Rat(25423) cathepsin C
- domestic guinea pig(100714387) cathepsin C
- naked mole-rat(101697606) cathepsin C
- dog(403458) cathepsin C
- domestic cat(101092140) cathepsin C
- sheep(101112686) cathepsin C
- Zebrafish(368704) cathepsin C
- chicken(419014) cathepsin C
- cow(352958) cathepsin C
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CTSC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Proteins
Numero di prodotto
Descrizione
Specie