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Merck

CILP

cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Sinonimi:
CILP-1, HsT18872
Specie:
ID UniProtKB:
ID gene:
  • Human(8483) Summary: Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
  • Mouse(214425) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Rat(315761) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Zebrafish(553329) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • cow(100336614) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Horse(100053337) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • domestic cat(101084795) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • dog(487603) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • sheep(101119218) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • chicken(415533) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • naked mole-rat(101723750) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • domestic guinea pig(100721580) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

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ELISA

N° Catalogo
Descrizione
Specie
Human CILP-1 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-CILP antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Anti-CILP antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human, mouse, rat
Applicazione
ELISA
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Cilp,
Specie
mouse
MISSION® esiRNA, targeting human CILP,
Specie
human