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Merck

CASP6

caspase 6, apoptosis-related cysteine peptidase

Sinonimi:
MCH2
Specie:
ID UniProtKB:
ID gene:
  • Human(839) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12368) caspase 6
  • Rat(83584) caspase 6
  • dog(487899) caspase 6, apoptosis-related cysteine peptidase
  • Zebrafish(552927) caspase 6, apoptosis-related cysteine peptidase
  • chicken(395477) caspase 6, apoptosis-related cysteine peptidase
  • naked mole-rat(101707090) caspase 6, apoptosis-related cysteine peptidase
  • domestic guinea pig(100713360) caspase 6, apoptosis-related cysteine peptidase
  • cow(538409) caspase 6, apoptosis-related cysteine peptidase
  • sheep(101119820) caspase 6, apoptosis-related cysteine peptidase
  • domestic cat(768261) caspase 6, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Caspase-6 Antibody, clone 3I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse
Applicazione
ELISA
affinity binding assay

western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-Caspase-6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunocytochemistry

western blot
Anti-Caspase-6 Antibody, clone 2W4G2, Rabbit Monoclonal, ,
Reattività con
mouse
Applicazione
immunofluorescence
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
N-Acetyl-Val-Glu-Ile-Asp-al, ~99% (HPLC), powder,
Specie
human
Caspase Inhibitor, ,
Specie
human
NSCI, ≥97% (HPLC), solid,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CASP6,
Specie
human
MISSION® esiRNA, targeting mouse Casp6,
Specie
mouse