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Merck

ANTXR1

anthrax toxin receptor 1

Sinonimi:
ATR, GAPO, TEM8
Specie:
ID UniProtKB:
ID gene:
  • Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
  • Mouse(69538) anthrax toxin receptor 1
  • Rat(362393) anthrax toxin receptor 1
  • naked mole-rat(101701494) anthrax toxin receptor 1
  • domestic guinea pig(100728514) anthrax toxin receptor 1
  • sheep(101108204) anthrax toxin receptor 1
  • Domestic Rabbit(100357637) anthrax toxin receptor 1
  • cow(616010) anthrax toxin receptor 1
  • domestic cat(101092930) anthrax toxin receptor 1
  • Horse(100061334) anthrax toxin receptor 1
  • dog(612601) anthrax toxin receptor 1
  • chicken(428199) anthrax toxin receptor 1

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-TEM8/Anthrax Toxin Receptor 1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-ANTXR1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-ATR antibody produced in rabbit, purified antibody (Ion exchange),
Reattività con
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-Phospho-ANTXR1-pY382 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
dot blot
Anti-ATR (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunocytochemistry

immunofluorescence

western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Antxr1,
Specie
mouse
MISSION® esiRNA, targeting human ANTXR1,
Specie
human