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Merck

ALDOB

aldolase B, fructose-bisphosphate

Sinonimi:
ALDB, ALDO2
Specie:
ID UniProtKB:
ID gene:
  • Human(229) Summary: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
  • Mouse(230163) aldolase B, fructose-bisphosphate
  • Rat(24190) aldolase B, fructose-bisphosphate
  • sheep(443440) aldolase B, fructose-bisphosphate
  • chicken(427308) aldolase B, fructose-bisphosphate
  • Zebrafish(321664) aldolase b, fructose-bisphosphate
  • dog(474787) aldolase B, fructose-bisphosphate
  • domestic cat(101097025) aldolase B, fructose-bisphosphate
  • Horse(100054480) aldolase B, fructose-bisphosphate
  • domestic guinea pig(100720708) aldolase B, fructose-bisphosphate
  • Domestic Rabbit(100328925) aldolase B, fructose-bisphosphate
  • naked mole-rat(101713582) aldolase B, fructose-bisphosphate
  • cow(515263) aldolase B, fructose-bisphosphate

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-ALDOB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-Aldob Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Reattività con
dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-ALDOB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Kits

N° Catalogo
Descrizione
Specie
Aldolase Activity Colorimetric Assay Kit, Sufficient for 100 Colorimetric tests,
Specie
mouse, human, rat

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human ALDOB,
Specie
human