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Merck

ABHD12

abhydrolase domain containing 12

Sinonimi:
ABHD12A, BEM46L2, C20orf22, PHARC, dJ965G21.2
Specie:
ID UniProtKB:
ID gene:
  • Human(26090) Summary: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
  • Mouse(76192) abhydrolase domain containing 12
  • Rat(499913) abhydrolase domain containing 12
  • chicken(421249) abhydrolase domain containing 12
  • Zebrafish(767657) abhydrolase domain containing 12
  • sheep(101106539) abhydrolase domain containing 12
  • cow(768242) abhydrolase domain containing 12
  • domestic cat(101091357) abhydrolase domain containing 12
  • dog(477004) abhydrolase domain containing 12
  • naked mole-rat(101716415) abhydrolase domain containing 12
  • domestic guinea pig(100729841) abhydrolase domain containing 12

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-ABHD12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-ABHD12 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-ABHD12 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, human, mouse, pig, rat
Applicazione
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human ABHD12,
Specie
human
MISSION® esiRNA, targeting mouse Abhd12,
Specie
mouse