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Key Documents

WH0196403M1

Sigma-Aldrich

Monoclonal Anti-DTX3 antibody produced in mouse

clone 4F10, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-FLJ34766, Anti-RNF154, Anti-deltex 3 homolog (Drosophila)

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100 μG
€489.00

€489.00

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100 μG
€489.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

€489.00

Please contact Customer Service for Availability

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4F10, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable

isotype

IgG3λ

GenBank accession no.

NM_178502

UniProt accession no.

Q8N9I9

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DTX3(196403)

General description

Deltex 3 homolog (DTX3) has a truncated domain 1 and a proline-rich region. The gene encoding it is localized on human chromosome 12q13.3.

Immunogen

DTX3 (NP_848597, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTT

Biochem/physiol Actions

Deltex 3 homolog (DTX3) acts as an E3 ubiquitin ligase.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
08004-4F10

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Kunihiko Takeyama et al.
The Journal of biological chemistry, 278(24), 21930-21937 (2003-04-03)
Members of the DTX (Deltex) family act as Notch signaling modifiers and may also regulate transcription through interactions with specific transcription factors. DTX proteins have a basic N terminus; a central proline-rich region; and a C-terminal RING finger domain, a
Kristian Almstrup et al.
Cell and tissue research, 322(1), 159-165 (2005-04-23)
Testicular cancer is the most common malignancy among men in the reproductive age and the incidence is increasing, probably caused by environmental factors. Most testicular cancers are testicular germ cell tumours and all originate from a carcinoma in situ (CIS)

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