SRP6299

CD71/TFRC/TFR human

recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE)

• Synonym(s): T9, TfR1, Trfr, p90, sTfR
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• biological source: human
• recombinant: expressed in HEK 293 cells
• tag: 6-His tagged (N-terminus)
• Assay: ≥92% (SDS-PAGE)
• form: lyophilized
• mol wt: calculated mol wt 76 kDa; observed mol wt 80-85 kDa (DTT-reduced. Protein migrates due to glycosylation. Cys 89 is the predicted N-terminus.)
• packaging: pkg of 10 and 50 μg; pkg of 10 μg
• UniProt accession no.: P02786
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TFRC(7037)

Description

General description

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Physical form

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable