SRP0479
GCN5 (727-837) human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
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100 μG
€711.00
€711.00
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100 μG
€711.00
About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
€711.00
Please contact Customer Service for Availability
biological source
human
recombinant
expressed in E. coli
Assay
≥90% (SDS-PAGE)
form
aqueous solution
mol wt
14.1 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KAT2A(2648)
General description
Human GCN5 or KAT2A containing bromodomain (GenBank Accession No. NM_021078) amino-acids 727 – 837 (end) with N-terminal HIS-tag, MW = 14.1 kDa, expressed in an E. coli expression system.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Donna A Santillan et al.
Cancer research, 66(20), 10032-10039 (2006-10-19)
A critical unanswered question about mixed lineage leukemia (MLL) is how specific MLL fusion partners control leukemia phenotype. The MLL-cyclic AMP-responsive element binding protein-binding protein (CBP) fusion requires both the CBP bromodomain and histone acetyltransferase (HAT) domain for transformation and
Shanshan Li et al.
The Journal of biological chemistry, 284(14), 9411-9417 (2009-02-17)
Bromodomains are acetyl lysine binding modules found in many complexes that regulate gene transcription. In budding yeast, the coactivator complex SAGA (Spt-Ada-Gcn5-acetyl-transferase) predominantly facilitates transcription of stress-activated genes and requires the bromodomain of the Gcn5 subunit for full activation of
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