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Key Documents

SRP0474

Sigma-Aldrich

ATAD2A (981-1108) human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

ANCCA, ATPase family, AAA domain containing 2, PRO2000

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

16.2 kDa

packaging

pkg of 100 μg

NCBI accession no.

NM_014109

UniProt accession no.

Q6PL18

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... ATAD2(29028)

General description

Human Bromodomain ATAD2A (GenBank Accession No. NM_014109) amino acids 981 – 1108 with N-terminal HIS-tag, MW = 16.2 kDa, expressed in an E. coli expression system.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C Caron et al.
Oncogene, 29(37), 5171-5181 (2010-06-29)
Cancer cells frequently express genes normally active in male germ cells. ATAD2 is one of them encoding a conserved factor harbouring an AAA type ATPase domain and a bromodomain. We show here that ATAD2 is highly expressed in testis as
Ekaterina V Kalashnikova et al.
Cancer research, 70(22), 9402-9412 (2010-09-25)
Chromatin coregulators are important factors in tumorigenesis and cancer progression. ANCCA is an AAA+ ATPase and a bromodomain-containing nuclear coactivator for the estrogen and androgen receptors that is crucial for assembly of chromatin-modifying complexes and proliferation of hormone-responsive cancer cells.

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