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Key Documents

SAB5702044

Sigma-Aldrich

Anti-JAK1 Antibody, clone 7Q1B2, Rabbit Monoclonal

Synonym(s):

JAK1A, JAK1B, JTK3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

7Q1B2, monoclonal

form

liquid

mol wt

130 kDa

species reactivity

rat, human, rat

concentration

0.53 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

GTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLAS

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... JAK1(3716)

General description

This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 600-700 of human JAK1 (P23458).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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