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Merck
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Key Documents

SAB4300591

Sigma-Aldrich

Anti-STAT2 (Ab-690) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-ISGF-3 antibody produced in rabbit, Anti-MGC59816 antibody produced in rabbit, Anti-P113 antibody produced in rabbit, Anti-STAT113 antibody produced in rabbit, Anti-signal transducer and activator of transcription 2, 113kDa antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

conjugate:
unconjugated
application:
IHC (p)
WB
clone:
polyclonal
species reactivity:
human
citations:
1
technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000
Pricing and availability is not currently available.

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~113 kDa

species reactivity

human

concentration

1 mg/mL

Immunogen

Peptide sequence around aa. 688-692 (R-K-Y-L-K), according to the protein STAT2.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

STAT2 encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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