Skip to Content
Merck
All Photos(1)

Documents

R6000

Sigma-Aldrich

Ribonuclease S from bovine pancreas

Grade XII-S

Synonym(s):

RNase S, pancreatic RNase, protease-modified RNase A

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
9001-99-4
EC Number:
232-646-6
MDL number:
MFCD00132188
UNSPSC Code:
12352204
NACRES:
NA.54

biological source

bovine pancreas

type

Grade XII-S

form

powder

specific activity

≥60 Kunitz units/mg solid

mol wt

13.7 kDa

storage temp.

−20°C

InChI

1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)

InChI key

CQOVPNPJLQNMDC-UHFFFAOYSA-N

Application

Ribonuclease S from bovine pancreas has been used in a study to assess the hybridase activity of human ribonuclease-1. Ribonuclease S from bovine pancreas has also been used in a study to investigate a new approach to obtaining high-activity RNase, DNase, cholesterolesterase, and trypsin from cattle pancreas.

Other Notes

Protease-modified RNase A

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A new approach to obtaining high-activity RNase, DNase, cholesterolesterase, and trypsin from cattle pancreas.
V V Khomov et al.
Doklady. Biochemistry and biophysics, 400, 61-64 (2005-04-26)
Beata Schmidt et al.
Journal of chromatography. A, 1018(2), 155-167 (2003-11-19)
The overall topic of the investigation was the separation of basic proteins by cation exchange displacement chromatography. For this purpose two principal column morphologies were compared for the separation of ribonuclease A and alpha-chymotrypsinogen, two proteins found in the bovine
Nicoletta Potenza et al.
Nucleic acids research, 34(10), 2906-2913 (2006-06-02)
Human ribonuclease-1 (hRNase-1) is an extracellular enzyme found in exocrine pancreas, blood, milk, saliva, urine and seminal plasma, which has been implicated in digestion of dietary RNA and in antiviral host defense. The enzyme is characterized by a high catalytic
The preparation of subtilisn-modified ribonuclease and the separation of the peptide and protein components.
F M RICHARDS et al.
The Journal of biological chemistry, 234(6), 1459-1465 (1959-06-01)
Evgeny Onischenko et al.
Cell, 171(4), 904-917 (2017-10-17)
Nuclear pore complexes (NPCs) are ∼100 MDa transport channels assembled from multiple copies of ∼30 nucleoporins (Nups). One-third of these Nups contain phenylalanine-glycine (FG)-rich repeats, forming a diffusion barrier, which is selectively permeable for nuclear transport receptors that interact with
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service