P8791

Polyglycine

mol wt 500-5,000

• Synonym(s): Glycine homopolymer
• CAS Number: 25718-94-9
• MDL number: MFCD00166375
• UNSPSC Code: 12352202
• eCl@ss: 32160406
• PubChem Substance ID: 24898980
• NACRES: NA.26

Properties

• form: lyophilized powder
• mol wt: 500-5,000
• color: white to light yellow
• mp: 300 °C
• storage temp.: −20°C
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Gene Information: rat ... Grin2a(24409)

Description

Application

Polyglycine has been used as an external intensity standard for measuring cross polarization (CP) nuclear magnetic resonance (NMR) spectrum measurements[1] and ion mobility mass spectrometry.[2] It is suitable for use as a model for UV resonance Raman spectroscopy studies.[3]

Biochem/physiol Actions

Polyglycine exists in two forms, namely the polyglycine I (PGI) with anti-parallel β-sheet structure and polyglycine II (PGII) with extended 31-helix. It is a most flexible polypeptide with minimal steric hindrance and its solubility increases in the presence of lithium ions.[3] It is present in mammals and plants. Polyglycine stretch associated with the chloroplast membrane protein, Toc5 is essential for envelop sorting.[4]

Preparation Note

Prepared by phosphorylation.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable