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EHU054231

Sigma-Aldrich

MISSION® esiRNA

targeting human BCL3

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20 μG
€193.00
50 μG
€342.00

€193.00

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20 μG
€193.00
50 μG
€342.00

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

€193.00

Please contact Customer Service for Availability

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTTCCTTCCTTCCCCATCTCCACCCGCCTTCCTGCCCTTTGCTGGGGTCCTCCGAGGCCCTGGCCGGCCGGTGCCCCCCTCCCCAGCTCCAGGAGGCAGCTGAGGGGGATGGGGGGGCAGATCTTGGACTCATGAGGAGGGGCCCCCCTGCCCTGTGGGGTCAACCCTTCTGGAAACTGTGAAGATCTCACTCTGCCCCCCCCCCCCATCTTCGGGACCAGGATTTGCACAGAAGCACATGCACCTACCCATACACCCCCTCTTCTGAGCACAGATGTTCCCCCATCTCGCTCCCTCCCAGGACTCTGACCCCAGCATTCTCAGGCACCAGTCCCTGTCCGGAATGCCACCCACATCTTCCATTTCCATGTCCCCTCCCAGAGCTGGTGGACCCAGGGAACAGCCACTCCCCTCCACTCTCTACCAGATAACTGAGGAGGGGAGAGGTG

Ensembl | human accession no.

ENSG00000069399

NCBI accession no.

NM_005178

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... BCL3(602) , BCL3(602)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Mikiko Tohyama et al.
European journal of immunology, 48(1), 168-179 (2017-09-14)
IL-22 induces STAT3 phosphorylation and mediates psoriasis-related gene expression. However, the signaling mechanism leading from pSTAT3 to the expression of these genes remains unclear. We focused on Bcl-3, which is induced by STAT3 activation and mediates gene expression. In cultured
SeungPil Yun et al.
Biomolecules & therapeutics, 26(5), 464-473 (2017-08-24)
Cripto is a small glycosylphosphatidylinositol-anchored signaling protein that can detach from the anchored membrane and stimulate proliferation, migration, differentiation, vascularization, and angiogenesis. In the present study, we demonstrated that Cripto positively affected proliferation and survival of mesenchymal stem cells (MSCs)
Kangsheng Tu et al.
Oncology reports, 35(4), 2382-2390 (2016-02-18)
Previous studies have demonstrated the aberrant expression and oncogenic role of B-cell CLL/lymphoma-3 (BCL-3) in human malignancies. However, the clinical significance of BCL-3 and its biological function in human hepatocellular carcinoma (HCC) remain unknown. In the present study, the expression
Xi Chen et al.
Cell death & disease, 7(12), e2508-e2508 (2016-12-03)
Transforming growth factor beta (TGFβ) signaling in breast cancer is selectively associated with pulmonary metastasis. However, the underlying mechanisms remain unclear. Here we show that Bcl-3, a member of the IκB family, serves as a critical regulator in TGFβ signaling
Jianheng Wu et al.
International journal of oncology, 49(6), 2471-2479 (2016-10-18)
Aberrant expression of oncogenes and/or tumor suppressors play fundamental roles in the pathogenesis of glioma. B-cell CLL/lymphoma 3 (BCL3) was previously found to be a putative proto-oncogene in human cancers and the decoy receptor DcR1 is induced in a p50/Bcl3-dependent
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