All Photos(4)
About This Item
Empirical Formula (Hill Notation):
C14H16N2O4S
CAS Number:
Molecular Weight:
308.35
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.26
To inquire about this product D0875, please contact your local Merck office or dealer. Contact Technical Service
Recommended Products
form
powder
technique(s)
ligand binding assay: suitable
storage temp.
−20°C
SMILES string
CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC(O)=O
InChI
1S/C14H16N2O4S/c1-16(2)12-7-3-6-11-10(12)5-4-8-13(11)21(19,20)15-9-14(17)18/h3-8,15H,9H2,1-2H3,(H,17,18)
InChI key
QHFXORCWAQTTGH-UHFFFAOYSA-N
Application
Dansylglycine, an HSA drug site II probe, is used for the differentiation and analysis of specific binding sites on serum albumin. Dansylglycine is used to generate chromophore-modified cyclodextrins for use in chemosensor development.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Laura H Lucas et al.
Journal of the American Chemical Society, 126(43), 14258-14266 (2004-10-28)
It is important to characterize drug-albumin binding during drug discovery and lead optimization as strong binding may reduce bioavailability and/or increase the drug's in vivo half-life. Despite knowing about the location of human serum albumin (HSA) drug binding sites and
M Petersson et al.
Journal of chromatography. B, Biomedical sciences and applications, 714(1), 39-46 (1998-09-24)
This paper describes sample enrichment in a single levitated droplet for capillary electrophoresis (CE) analysis. The droplet was trapped in an acoustical field. The minute sample volumes needed for the enrichment procedure were precisely handled using a piezoelectric flow-through liquid
A Tamura et al.
Journal of pharmaceutical and biomedical analysis, 15(9-10), 1477-1482 (1997-06-01)
Separation process in a liquid chromatographic column were visualized and analyzed by a developed chromato-videoscope. The migration aspects were evaluated with successively obtained densitograms. In reversed-phase chromatography, the band widths of each solute band were almost equal fore both weakly
J Bramhall
Biochemistry, 25(13), 3958-3962 (1986-07-01)
The amphiphilic fluorescent dye N-[(5-dimethylamino)naphth-1-ylsulfonyl]glycine (dansylglycine) can be used to monitor the magnitude and stability of transmembrane proton gradients. Although freely soluble in aqueous media, the dye readily adsorbs to the surfaces of lipid vesicles. Because membrane-bound dye fluoresces at
Eva A Enyedy et al.
Bioorganic & medicinal chemistry, 19(14), 4202-4210 (2011-06-24)
The specific binding of carrier ligands of antidiabetic vanadium(IV) and zinc(II) complexes into drug binding pockets of human serum albumin (HSA) has been investigated via displacement reactions of site markers such as warfarin and dansylglycine by different spectroscopic (fluorescence, circular
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
