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85541

Sigma-Aldrich

L-(−)-Sorbose

for biotechnological purposes, ≥98.0% (sum of enantiomers, HPLC)

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1724554
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

grade

for biotechnological purposes

Quality Level

Assay

≥98.0% (sum of enantiomers, HPLC)

form

solid

optical activity

[α]20/D −43±2°, c = 5% in H2O

color

colorless

mp

163-165 °C

solubility

H2O: 0.1 g/mL, clear, colorless to very faintly yellow

SMILES string

OC[C@H](O)[C@@H](O)[C@H](O)C(=O)CO

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5+,6+/m0/s1

InChI key

BJHIKXHVCXFQLS-OTWZMJIISA-N

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Application

L-Sorbose is used as a starting reagent for the commercial biosynthesis of ascorbic acid (vitamin C).

Biochem/physiol Actions

The L enatiomer of sorbose, a ketohexose monosaccharide.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xia Ke et al.
Journal of biotechnology, 300, 55-62 (2019-05-18)
6-(N-hydroxyethyl) amino-6-deoxy-l-sorbofuranose (6NSL) is the direct precursor of miglitol for diabetes therapy. The regio- and stereo-selective dehydrogenation offered by the membrane-bound d-sorbitol dehydrogenase (mSLDH) from Gluconobacter oxydans provides an elegant enzymatic method for 6NSL production. In this study, two subunits
Cai-Hui Pan et al.
Journal of industrial microbiology & biotechnology, 44(7), 1031-1040 (2017-03-12)
Defect in the amino acid biosynthetic pathways of Ketogulonicigenium vulgare, the producing strain for 2-keto-L-gulonic acid (2-KGA), is the key reason for its poor growth and low productivity. In this study, five different strains were firstly reconstructed by expressing absent
Hans K Carlson et al.
The ISME journal, 14(8), 2034-2045 (2020-05-07)
Respiratory and catabolic genes are differentially distributed across microbial genomes. Thus, specific carbon sources may favor different respiratory processes. We profiled the influence of 94 carbon sources on the end products of nitrate respiration in microbial enrichment cultures from diverse
Mengzhu Li et al.
AMB Express, 8(1), 38-38 (2018-03-15)
Pyranose oxidase (POx) is a homotetrameric flavoprotein that catalyzes the oxidation of pyranose-configured sugars at position C-2 to corresponding 2-ketoaldoses. The wide substrate specificity makes POx potential for application in various biotechnological industries. In the present study we reported the
Yue Chen et al.
Frontiers in bioengineering and biotechnology, 7, 385-385 (2020-01-11)
High-throughput screening is a powerful tool for discovering strains in the natural environment that may be suitable for target production. Herein, a novel enzyme-based high-throughput screening method was developed for rapid screening of strains overproducing 2-keto-L-gulonic acid (2-KLG). The screening

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