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S0800000

Sodium salicylate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

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About This Item

Linear Formula:
HOC6H4COONa
CAS Number:
54-21-7
Molecular Weight:
160.10
Beilstein:
3732792
MDL number:
MFCD00002440
UNSPSC Code:
41116107
PubChem Substance ID:
329824441
NACRES:
NA.24

grade

pharmaceutical primary standard

Agency

EP Reference Standard

API family

sodium salicylate

manufacturer/tradename

EDQM

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

InChI key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sodium salicylate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H319,H361d

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

208.9 °F - Pensky-Martens closed cup

Flash Point(C)

98.3 °C - Pensky-Martens closed cup

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Marisa Wickerath et al.
Anticancer research, 34(7), 3399-3401 (2014-07-02)
The standard methods of chemotherapy in cancer treatment are expensive and pose serious health effects. The present study investigates an alternative chemotherapy by testing the combined treatment of two drugs on leukemia cells: dihydroartemisinin (DHA) and sodium salicylate (SS). Cells
Rainer Amann et al.
European journal of pharmacology, 447(1), 1-9 (2002-07-11)
Aspirin (acetylsalicylic acid) is one of the most widely used drugs worldwide. It acetylates cyclooxygenases thereby irreversibly blocking the conversion of arachidonic acid to prostanoids. Biotransformation of aspirin yields salicylate, a compound that possesses similar anti-inflammatory potency as aspirin but
I V Petrova et al.
Farmakologiia i toksikologiia, 43(2), 184-186 (1980-03-01)
It is established in in-vitro experiments that mefenamic acid and sodium salicylate inhibit to an equal measure the cell immunity test, a reaction of blast transformation of lymphocytes. The effect increases with the higher concentration of the drugs under study
Kulthida Vaeteewoottacharn et al.
Anticancer research, 34(4), 1865-1871 (2014-04-03)
Primary effusion lymphoma (PEL) is a rare but aggressive form of non-Hodgkin's B-cell lymphoma in immunodeficient patients. Resistance to conventional chemotherapeutic regimens is common in PEL and contributes to a very poor prognosis; hence, novel potent anti-PEL agents are required.
Mark Zander et al.
Plant physiology, 165(4), 1671-1683 (2014-07-06)
Salicylic acid (SA), a hormone essential for defense against biotrophic pathogens, triggers increased susceptibility of plants against necrotrophic attackers by suppressing the jasmonic acid-ethylene (ET) defense response. Here, we show that this disease-promoting SA effect is abolished in plants lacking
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