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A156

Supelco

(±)-N-Allylnormetazocine hydrochloride

analytical standard

Synonym(s):

(2α,6α)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol

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About This Item

Empirical Formula (Hill Notation):
C17H23NO · HCl
CAS Number:
7619-35-4
Molecular Weight:
293.83
MDL number:
MFCD00151708
UNSPSC Code:
41116107
PubChem Substance ID:
329770714
NACRES:
NA.24

grade

analytical standard

Quality Level

100

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.[H]C1(C)C2Cc3ccc(O)cc3C1(C)CCN2CC=C

InChI

1S/C17H23NO.ClH/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17;/h4-6,11-12,16,19H,1,7-10H2,2-3H3;1H

InChI key

ZTGMHFIGNYXMJV-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
FE09071801
FE12092105
097H4669

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Felix J Kim et al.
Biochemical and biophysical research communications, 426(2), 177-182 (2012-08-29)
Treatment with sigma1 receptor (Sigma1) ligands can inhibit cell proliferation in vitro and tumor growth in vivo. However, the cellular pathways engaged in response to Sigma1 ligand treatment that contribute to these outcomes remain largely undefined. Here, we show that
Christopher P Palmer et al.
Cancer research, 67(23), 11166-11175 (2007-12-07)
Lipid rafts are membrane platforms that spatially organize molecules for specific signaling pathways that regulate various cellular functions. Cholesterol is critical for liquid-ordered raft formation by serving as a spacer between the hydrocarbon chains of sphingolipids, and alterations in the
Yukio Ago et al.
Psychopharmacology, 217(3), 377-386 (2011-04-14)
Fluvoxamine, a selective serotonin (5-HT) reuptake inhibitor (SSRI) and an agonist for the σ(1) receptors, increases extracellular monoamines in the prefrontal cortex, but it is not known whether the σ(1) receptor is involved in the neurochemical effect of fluvoxamine. In
Mitsuo Tanabe
Neuropharmacology, 53(3), 406-414 (2007-07-17)
Using whole-cell voltage-clamp recordings, hyperpolarization-activated cation currents (Ih) were elicited with hyperpolarizing voltage jumps in CA1 pyramidal neurons of rat hippocampal slices, and the effects of phencyclidine (PCP) and some sigma ligands on Ih were studied. PCP concentration-dependently (0.1-100 microM)
Vân-Ly Phan et al.
Journal of neuroscience research, 79(4), 561-572 (2005-01-07)
The sigma1 receptor is a unique intracellular receptor whose activation results in an efficient modulation of several neurotransmitter responses. Its role as a target for the rapid nongenomic effects of neuro(active)steroids and the age-related diminutions in steroid levels suggested that
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