56781
Iminodiacetic acid
≥98.0% (T), for peptide synthesis
Synonym(s):
IDA
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product name
Iminodiacetic acid, purum, ≥98.0% (T)
grade
purum
Quality Level
Assay
≥98.0% (T)
form
solid
mp
243 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
OC(=O)CNCC(O)=O
InChI
1S/C4H7NO4/c6-3(7)1-5-2-4(8)9/h5H,1-2H2,(H,6,7)(H,8,9)
InChI key
NBZBKCUXIYYUSX-UHFFFAOYSA-N
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Application
Iminodiacetic acid (IDA) can be used as a tridentate ligand to chelate metal ions. Some of the common applications of IDA include:
- Synthesis of N-methyliminodiacetic acid (MIDA), which is an essential precursor for the synthesis of highly versatile MIDA boronates for cross coupling reactions.
- Synthesis of metal complexes of iminodiacetic acid with a radionuclide, especially 99mTc are as radiotracers for cholescintigraphy scans and for radiopharmaceutical applications.
- Synthesis of lanthanide hybrid frameworks via self-assembly of lanthanide ions (Ln3+) with iminodiacetic acid under hydrothermal conditions.
- Preparation of a thermosensitive macroporous protein-imprinted hydrogel for the recognition of protein by metal coordinate interaction.
- Synthesis of IDA functionalized styrene-divinyl benzene co-polymeric beads for the removal of heavy metal ions like Cd(II), Cr(VI), Ni(II) and Pb(II) from their aqueous solutions.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Iminodiacetic acid functionalized cation exchange resin for adsorptive removal of Cr (VI), Cd (II), Ni (II) and Pb (II) from their aqueous solutions.
Journal of Hazardous Materials, 185(2-3), 1508-1512 (2011)
General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates.
Organic Letters, 12(10), 2314-2317 (2010)
Influence of the Denticity of Ligand Systems on the in vitro and in vivo Behavior of 99mTc (I)-Tricarbonyl Complexes: A Hint for the Future Functionalization of Biomolecules.
Bioconjugate Chemistry, 11(3), 345-351 (2000)
Der chelateffekt.
Helvetica Chimica Acta, 35(7), 2344-2359 (1952)
Serendipity in technetium-99m dimethyl iminodiacetic acid cholescintigraphy: diagnosis of nonbiliary disorders in suspected acute cholecystitis.
Radiology, 135(2), 449-454 (1980)
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