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36663

Supelco

2,4′-DDE solution

100 μg/mL in methanol, PESTANAL®, analytical standard

Synonym(s):

2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethene solution

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About This Item

Empirical Formula (Hill Notation):
C14H8Cl4
CAS Number:
3424-82-6
Molecular Weight:
318.03
Beilstein:
1977640
EC Number:
200-659-6
MDL number:
MFCD00036122
UNSPSC Code:
41116107
PubChem Substance ID:
329755437
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture

format

single component solution

storage temp.

2-8°C

SMILES string

Clc1ccc(cc1)\C(=C(\Cl)Cl)c2ccccc2Cl

InChI

1S/C14H8Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8H

InChI key

ZDYJWDIWLRZXDB-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

51.8 °F

Flash Point(C)

11 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3302
BCCF5625
BCCC1817
BCBR9642V
SZBE029XV

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Mitotane ≥98% (HPLC)

Sigma-Aldrich

SML1885

Mitotane

Ilse G Hermsen et al.
The Journal of clinical endocrinology and metabolism, 96(6), 1844-1851 (2011-04-08)
In patients with adrenocortical carcinoma (ACC) mitotane activity has been suggested to depend on plasma levels 14 mg/liter or greater and metabolite formation. The study was performed to confirm the correlation of the currently used mitotane (o,p'DDD) threshold of 14
D B Carlson et al.
Environmental health perspectives, 108(3), 249-255 (2000-03-08)
Fish sexual development is sensitive to exogenous hormone manipulation, and salmonids have been used extensively as environmental sentinels and models for biomedical research. We simulated maternal transfer of contaminants by microinjecting rainbow trout (Oncorhynchus mykiss) and chinook salmon (Oncorhynchus tshawytscha)
P Balaguer et al.
The Science of the total environment, 233(1-3), 47-56 (1999-09-24)
In order to characterize the estrogenic activity of chemicals, we established complementary in vitro recombinant receptor-reporter gene assays in stably transfected MCF-7 and HeLa cells. MCF-7 cells which express the endogenous estrogen receptor alpha (ER alpha) were stably transfected with
R Benecke et al.
European journal of clinical pharmacology, 41(3), 259-261 (1991-01-01)
Mitotane (o,p'-DDD) can be used for the treatment of various adrenocortical diseases such as Cushing's syndrome, but the usual doses of 6-8 g per day are often associated with severe adverse effects. This paper reports the results of much lower
Anna A Kasperlik-Zaluska et al.
Journal of experimental therapeutics & oncology, 5(2), 125-132 (2006-02-14)
Our study aimed at evaluation of the relations between the plasma levels of mitotane (o,p'-DDD) and its metabolites, o,p'-DDA and o,p'-DDE, and the efficacy of Mitotane therapy during a long-term follow-up. Eighteen patients, aged 11 to 70 years, were included
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