03582
1-(Boc-amino)cyclohexanecarboxylic acid
≥98.0% (TLC)
Synonym(s):
Boc-homocycloleucine
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About This Item
Linear Formula:
(CH3)3CO2CNHC6H10CO2H
CAS Number:
Molecular Weight:
243.30
Beilstein:
4189683
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
≥98.0% (TLC)
form
powder with small lumps
reaction suitability
reaction type: Boc solid-phase peptide synthesis
color
white
mp
176-178 °C (dec.)
application(s)
peptide synthesis
SMILES string
CC(C)(C)OC(=O)NC1(CCCCC1)C(O)=O
InChI
1S/C12H21NO4/c1-11(2,3)17-10(16)13-12(9(14)15)7-5-4-6-8-12/h4-8H2,1-3H3,(H,13,16)(H,14,15)
InChI key
URBHKVWOYIMKNO-UHFFFAOYSA-N
Other Notes
Synthesis of modified peptides
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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P Furet et al.
Bioorganic & medicinal chemistry letters, 10(20), 2337-2341 (2000-10-31)
Based on X-ray crystal structure information, mono charged phosphinate isosteres of phosphotyrosine have been designed and incorporated in a short inhibitory peptide sequence of the Grb2-SH2 domain. The resulting compounds, by exploiting additional interactions, inhibit binding to the Grb2-SH2 domain
M Mazzeo et al.
Journal of peptide science : an official publication of the European Peptide Society, 1(5), 330-340 (1995-09-01)
The cyclic octapeptide cyclo[-Pro1-Pro-Phe-Phe-Ac6c-Ile-ala-Val8-] [C8-Ac6c], containing the Pro1-Pro-Phe-Phe sequence, followed by a bulky helicogenic C alpha,alpha-dialkylated glycine residue Ac6c [1-aminocyclohexane-1-carboxylic acid), and a D-Ala residue at position 7 has been synthesized. This cyclic peptide is a deletion analogue of the
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