Sox-2 plays a key role in embryonic stem cell development, and has been shown to help stem cells maintain a pluripotent potential. It has also been shown to be associated with uncommitted dividing stem cell and precursor cells of the developing CNS.
Specificity
SOX-2
Application
Anti-SOX-2 Antibody, clone 6G1.2, FITC conjugate is an antibody against SOX-2 for use in FC.
Quality
Evaluated by flow cytometry on undifferentiated adult Rat hippocampal neural stem cells SCR022. Optimal working dilutions must be determined by the end user.
Target description
~34 kDa
Physical form
Purified mouse monoclonal IgG2b conjugated to FITC in PBS with less than 0.09% sodium azide and 15 mg/mL BSA.
Analysis Note
Control Rat Neural Stem Cells.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Biotechnology and bioengineering, 117(5), 1316-1328 (2020-01-22)
Embryonic stem cells (ESCs) have almost unlimited proliferation capacity in vitro and can retain the ability to contribute to all cell lineages, making them an ideal platform material for cell-based therapies. ESCs are traditionally cultured in static flasks on a
American journal of cancer research, 10(10), 3487-3506 (2020-11-10)
Breast cancer remains a complex disease resulting in high mortality in women. A subset of cancer stem cell (CSC)-like cells expressing aldehyde dehydrogenase 1 (ALDH1) and SOX2/OCT4 are implicated in aggressive biology of specific subtypes of breast cancer. Targeting these
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