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ABF295

Sigma-Aldrich

Anti-IL27RA Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Interleukin-27 receptor subunit alpha, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, IL-27RA, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, TCCR, ZcytoR1, IL27RA

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... IL27RA(9466)

General description

IL27RA (also known as Interleukin-27 receptor subunit alpha, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, TCCR and ZcytoR1) is a receptor for IL27 and requires IL6ST/gp130 to mediate signal transduction in response to IL27 binding. IL27RA is involved in the regulation of Th1-type immune responses and appears to be involved in innate defense mechanisms. IL27RA is predominately expressed in thymus, spleen, lymph nodes and peripheral blood leukocytes.

Immunogen

Epitope: N-terminus
KLH-conjugated linear peptide corresponding to amino acids near the N-terminus of human IL27RA.

Application

Anti-IL27RA Antibody is a highly specific rabbit polyclonal antibody, that targets IL27RA & has been tested in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 10 μg/mL from a representative lot detected IL27RA in human spleen tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected IL27RA in A549 cells.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

Quality

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected IL27RA in human spleen tissue lysate.

Target description

~69 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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