850582P
Avanti
Laurdan
Avanti Research™ - A Croda Brand
Synonym(s):
1-(6-(dimethylamino)naphthalen-2-yl)dodecan-1-one, 6-dodecanoyl-2-dimethylaminonaphthalene
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About This Item
Empirical Formula (Hill Notation):
C24H35NO
CAS Number:
Molecular Weight:
353.54
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
Assay
99% (TLC)
form
powder
packaging
package of 1 × 100 μg
package of 1 × 500 μg
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
1-(6-(dimethylamino)naphthalen-2-yl) dodecan-1-one or Laurdan is a derivative of naphthalene and is a fluorescent membrane probe. It is present at the hydrophilic-hydrophobic interface of the lipid bilayer, wherein the lauric acid tail is attached attached in the phospholipid acyl chain area.
Biochem/physiol Actions
1-(6-(dimethylamino)naphthalen-2-yl) dodecan-1-one or Laurdan exhibits spectral sensitivity to phospholipid phase state. It also exhibits fluorescence property. Laurdan is implicated in bilayer property studies of natural and artificial membranes due to its sensitivity to solvent relaxation effect.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850582p-100UG) 2 mL Amber Serum Vial with Stopper and Crimp Cap (850582p-500UG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Laurdan and Prodan as polarity-sensitive fluorescent membrane probes
Parasassi T, et al.
Journal of Fluorescence, 8(4), 365-373 (1998)
Two-photon fluorescence microscopy of laurdan generalized polarization domains in model and natural membranes
Parasassi T, et al.
Biophysical Journal, 72(6), 2413-2429 (1997)
Use of laurdan fluorescence intensity and polarization to distinguish between changes in membrane fluidity and phospholipid order
Harris F M, et al.
Biochimica et Biophysica Acta - Biomembranes, 1565(1), 123-128 (2002)
Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence.
Parasassi T, et al.
Biophysical Journal, 60(1), 179-179 (1991)
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