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840055C

Avanti

Liver PC

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylcholine (Liver, Bovine)

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25 MG
€574.00

€574.00

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25 MG
€574.00

About This Item

CAS Number:
475662-36-3
MDL number:
MFCD00082428
UNSPSC Code:
12352211
NACRES:
NA.25

€574.00

Please contact Customer Service for Availability
Request a Bulk Order

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840055C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (840055C-25mg)

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid found in mammalian membranes. It consists of a positively charged quaternary amine in the headgroup and a negatively charged phosphate group.[1]

Application

Liver PC is suitable for use:
  • in the preparation of two dimensional crystals of microsomal glutathione transferase 1 for electron microscopy[2]
  • in the preparation of ′golgi lipid′ mixture for liposome recruitment assay[3]
  • in lipid vesicle preparation for ligand transfer assay[4]

Biochem/physiol Actions

Phosphatidylcholine (PC) is an important source of diacylglycerol and other signaling molecules.[5] Liver PC has a saturated to unsaturated fatty acid ratio of 0.91.[6]

Packaging

5 mL Clear Glass Sealed Ampule (840055C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

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Stress sensor triggers conformational response of the integral membrane protein microsomal glutathione transferase 1
Busenlehner LS, et al.
Biochemistry, 43(35), 11145-11152 (2004)
GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation
Witkos TM, et al.
Nature Communications, 10(1), 127-127 (2019)
The Membranes of Cells (2016)
Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein
Zhang WX, et al.
Lipids, 44(7), 631-631 (2009)
The contribution of surface residues to membrane binding and ligand transfer by the alpha-tocopherol transfer protein (alpha-TTP)
Zhang WX, et al.
Journal of molecular biology, 405(4), 972-988 (2011)
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