810173P
Avanti
16:0-06:0 NBD PA
Avanti Research™ - A Croda Brand 810173P, powder
Synonym(s):
1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphate (ammonium salt)
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About This Item
Empirical Formula (Hill Notation):
C31H54N5O11P
CAS Number:
Molecular Weight:
703.76
UNSPSC Code:
12352211
NACRES:
NA.25
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810173P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810173P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidic acid (PA) is a simple anionic membrane phospholipid. The phospholipid contains phosphomonoester polar head group and two long hydrophobic acyl chains. 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) PA is a fluorescent analog with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) attached to the sn-2 fatty acid of PA.
Application
16:0-06:0 NBD PA 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphate is suitable to measure the substrate transport by an increase in cellular fluorescence to determine type 4 P-type ATPases (P4-ATPase) discrimination and its glycerophospholipid (GPL) substrate selection through the directed evolution of a sphingomyelin (SM) flippase.
Biochem/physiol Actions
Phosphatidic acid (PA) is crucial for intracellular signaling involved various cellular processes including membrane trafficking and sperm hyper-activation. It plays a vital role in lipid synthesis.
Packaging
5 mL Amber Glass Screw Cap Vial (810173P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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