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T46108

Sigma-Aldrich

1,2,4-Triazole

98%

Synonym(s):

3,4-Diazapyrrole, 4H-1,2,4-Triazole, s-Triazole (8CI)

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€37.10
100 G
€92.30
500 G
€218.00

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25 G
€37.10
100 G
€92.30
500 G
€218.00

About This Item

Empirical Formula (Hill Notation):
C2H3N3
CAS Number:
Molecular Weight:
69.07
Beilstein:
104767
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay:
98%

€37.10


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Request a Bulk Order

Quality Level

Assay

98%

bp

260 °C (lit.)

mp

119-121 °C (lit.)

SMILES string

c1nc[nH]n1

InChI

1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)

InChI key

NSPMIYGKQJPBQR-UHFFFAOYSA-N

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Application

1,2,4-triazole and its derivatives are important structural moieties of many pharmaceutical drugs.[1] Triazoles can also act as ligands to form coordination complexes with transition metal ions.[2] Due to their electron-deficient nature, they exhibit excellent electron-transport and hole-blocking properties, making them promising organic materials in material science applications.[3]

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mononuclear, oligonuclear and polynuclear metal coordination compounds with 1, 2, 4-triazole derivatives as ligands.
Haasnoot JG
Coordination Chemistry Reviews, 200, 131-185 (2000)
Applications of Metal-Free 1, 2, 4-Triazole Derivatives in Materials Science.
Diaz-Ortiz A
Current Organic Chemistry, 19(7), 568-584 (2015)
1, 2, 4-Triazoles: Synthetic approaches and pharmacological importance.
Al-Masoudi IA
Chemistry of Heterocyclic Compounds, 42(11), 1377-1403 (2006)
Camila C Amorim et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 48(3), 183-190 (2013-01-30)
This study evaluated the adsorption capacity of ethylenthiourea (ETU) and 1H-1,2,4-triazole (1,2,4-T) for two commercial activated carbons: charcoal-powdered activated carbon (CPAC) and bovine bone-powdered activated carbon (BPAC). The tests were conducted at a bench scale, with ETU and 1,2,4-T diluted
Aline Moulin et al.
Amino acids, 44(2), 301-314 (2012-07-17)
Ghrelin is a 28-residue peptide acylated with an n-octanoyl group on the Ser 3 residue, predominantly produced by the stomach. Ghrelin displays strong growth hormone (GH) releasing activity, which is mediated by the activation of the so-called GH secretagogue receptor

Questions

1–5 of 5 Questions  
  1. What is the solubility of 1,2,4-Triazole (Product No. T46108)?

    1 answer
    1. Triazole is appreciably soluble in water and alcohol, according to the 14th edition of the chemicals encyclopedia published by the Royal Society of Chemistry.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. What type of information is available for derivatives of 1,2,4-triazole (Product No. T46108)?

    1 answer
    1. A good source for information on 1,2,4-triazoles is a review article by K.T. Potts entitled The Chemistry of 1,2,4-Triazoles. Here is the citation: Chem. Rev., 61(2), 87-127 (1961).

      Helpful?

  4. How is Product No. T46108, 1,2,4-Triazole, produced?

    1 answer
    1. Typically the exact production methods are considered proprietary; this is also true for product T46108.  The 1,2,4-Triazole preparation is outlined in this article by C. Ainsworth: Org. Synth., 40, 99 (1960).

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  5. How is Product No. T46108, 1,2,4-Triazole, packaged?

    1 answer
    1. Product No. T46108 is typically packaged in a high density polyethylene (HDPE) bottle with a Teflon-lined polypropylene (PP) cap.

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