Anti-cancer agents in medicinal chemistry, 18(12), 1770-1778 (2018-05-26)
In this study, new azafluorenones, 4-(4-fluorophenyl)-2-(4-substitutedphenyl)-5Hindeno[ 1,2-b] pyridin-5-one, I1-I8 were synthesized and chemical structures were elucidated by spectral analysis. All compounds were reported for the first time here. Compounds were tested in terms of cytotoxicity. They were found as cytotoxins/anticancer
Journal of fluorescence, 27(1), 135-150 (2016-10-04)
Novel bioactive complexes of Co(II), Cu(II), Ni(II) and Zn(II) metal ions with Schiff base ligand derived from histidine and 1,3-indandione were synthesized and thoroughly characterized by various analytical and spectral techniques. The biological investigations were carried out to examine the
Bollettino della Societa italiana di biologia sperimentale, 60(1), 79-84 (1984-01-30)
In order to obtain biologically active compounds with a probable anticoagulant activity, some new products, by Michael method from indandione and 2-phenylindandione with ethyl alpha-cyano-beta-aryl-acrylates, have been prepared. The reaction of phenylindandione with methylvinylketone has been also carried out. The
[Effect of anticoagulants of the 4-hydroxycoumarin derivative group on aminotransferase activity in vitro and in vivo].
N-Substituted indan-1.3-diones have proven to be potent cytotoxic agents effective against the growth of single cell leukemia tumors and cell lines derived from solid tumors. A number of the derivatives were active against growth of solid tumors e.g. colon, lung
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