390674

5-(Trifluoromethoxy)isatin

98%

• Synonym(s): 5-(Trifluoromethoxy)indoline-2,3-dione
• Empirical Formula (Hill Notation): C₉H₄F₃NO₃
• CAS Number: 169037-23-4
• Molecular Weight: 231.13
• MDL number: MFCD00192524
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864336

Properties

• Assay: 98%
• mp: 170-172 °C (lit.)
• SMILES string: FC(F)(F)Oc1ccc2NC(=O)C(=O)c2c1
• InChI: 1S/C9H4F3NO3/c10-9(11,12)16-4-1-2-6-5(3-4)7(14)8(15)13-6/h1-3H,(H,13,14,15)
• InChI key: XHAJMVPMNOBILF-UHFFFAOYSA-N

Description

Application

Reactant for preparation of (fluorinated-indolinonylidene)-hydrazine-carbothioamides by condensation with thiosemicarbazides
Reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors
Reactant for preparation of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors
Reactant for synthesis of ortho disubstituted biphenyls
Reactant for preparation of indolinon-spirothiazolidinones as selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
Reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors
Reactant for preparation of indolone acetamides as antiseizure agents

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable