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222909

Sigma-Aldrich

N-Phenylthiourea

97%

Synonym(s):

1-Phenyl-2-thiourea, PTU, Phenylthiocarbamide

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About This Item

Linear Formula:
C6H5NHCSNH2
CAS Number:
103-85-5
Molecular Weight:
152.22
Beilstein:
907309
EC Number:
203-151-2
MDL number:
MFCD00004933
UNSPSC Code:
12352100
PubChem Substance ID:
329752296

Assay

97%

mp

145-150 °C (lit.)

SMILES string

NC(=S)Nc1ccccc1

InChI

1S/C7H8N2S/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10)

InChI key

FULZLIGZKMKICU-UHFFFAOYSA-N

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Description
Pricing

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300,H317

Hazard Classifications

Acute Tox. 1 Oral - Skin Sens. 1

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Anna A Brozyna et al.
International journal of cancer, 123(6), 1448-1456 (2008-06-21)
Melanin pigment displays strong photo- and radioprotective properties, suggesting that inhibition melanogenesis could increase sensitivity of melanoma to ionizing radiation. We tested this concept in human melanoma cells cultured in either Ham's F10 medium to maintain amelanotic phenotype or DMEM
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Blood, 125(19), 2974-2984 (2015-03-18)
Isocitrate dehydrogenase 1 mutation (IDH1-R132H) was recently identified in acute myeloid leukemia with normal cytogenetics. The mutant enzyme is thought to convert α-ketoglutarate to the pathogenic 2-hydroxyglutarate (2-HG) that affects DNA methylation via inhibition of ten-eleven translocation 2. However, the
Marco Venturin et al.
Journal of medical genetics, 51(7), 436-443 (2014-04-09)
Cardiovascular malformations have a higher incidence in patients with NF1 microdeletion syndrome compared to NF1 patients with intragenic mutation, presumably owing to haploinsufficiency of one or more genes included in the deletion interval and involved in heart development. In order
Thomas Grau et al.
Antimicrobial agents and chemotherapy, 56(2), 1142-1145 (2011-11-23)
Ethionamide (ETH) is a second-line drug for the treatment of tuberculosis. As a prodrug, ETH has to be activated by EthA. ethA is controlled by its repressor EthR. 2-Phenylethyl-butyrate (2-PEB) inhibits EthR binding, enhances expression of EthA, and thereby enhances
Warrick J Brewer et al.
Psychiatry research, 199(1), 8-11 (2012-04-17)
Reports suggesting that schizophrenia participants are more likely to be phenylthiocarbamide (PTC) non-tasters when compared to controls have recently been controversial. If supported, a genetic-based phenotypic variation in PTC taster status is implicated, suggesting a greater illness risk for those
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