196932
3-Methoxy-5-(trifluoromethyl)aniline
99%
Synonym(s):
5-Methoxy-α,α,α-trifluoro-m-toluidine
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
CH3OC6H3(CF3)NH2
CAS Number:
Molecular Weight:
191.15
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
To inquire about this product 196932, please contact your local Merck office or dealer. Contact Technical Service
Recommended Products
Assay
99%
form
solid
mp
50-52 °C (lit.)
functional group
fluoro
SMILES string
COc1cc(N)cc(c1)C(F)(F)F
InChI
1S/C8H8F3NO/c1-13-7-3-5(8(9,10)11)2-6(12)4-7/h2-4H,12H2,1H3
InChI key
VTFGJEYZCUWSAM-UHFFFAOYSA-N
Application
3-Methoxy-5-(trifluoromethyl)aniline was used in the synthesis of spleen tyrosine kinase inhibitors based on the phenylamino pyrimidine thiazole[1].
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Luc J Farmer et al.
Bioorganic & medicinal chemistry letters, 18(23), 6231-6235 (2008-10-22)
A series of SYK inhibitors based on the phenylamino pyrimidine thiazole lead 4 were prepared and evaluated for biological activity. Lead optimization provided compounds with nanomolar K(i)'s against SYK and potent inhibition in mast cell degranulation assays.
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
