146064

β-Alanine

99%, suitable for ligand binding assays

• Synonym(s): β-Ala, 3-Aminopropionic acid
• Linear Formula: NH₂CH₂CH₂COOH
• CAS Number: 107-95-9
• Molecular Weight: 89.09
• Beilstein: 906793
• EC Number: 203-536-5
• MDL number: MFCD00008200
• UNSPSC Code: 12352209
• eCl@ss: 39030936
• PubChem Substance ID: 24848760
• NACRES: NA.26

Properties

• product name: β-Alanine, 99%
• Assay: 99%
• form: powder, crystals or granules
• technique(s): ligand binding assay: suitable
• color: white
• mp: 202 °C (dec.) (lit.)
• application(s): peptide synthesis
• SMILES string: NCCC(O)=O
• InChI: 1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
• InChI key: UCMIRNVEIXFBKS-UHFFFAOYSA-N

Description

Application

β-Alanine has been used as a ligand for the orphan MAS-related receptor. It has also been used in culture media used for certain strains of yeast to test for β-alanine auxotrophy.

Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves