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T6830

Thyroglobulin human

Synonym(s):

Thyroglobulin human

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About This Item

CAS Number:
9010-34-8
UNSPSC Code:
12352202
EC Number:
232-721-3
NACRES:
NA.56
MDL number:
MFCD01324794
Form:
lyophilized solid
Assay:
≥95% (SDS-PAGE)
Biological source:
human
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biological source

human

Quality Segment

assay

≥95% (SDS-PAGE)

form

lyophilized solid

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... TG(7038)

General description

Human Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Human Thyroglobin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyryonine. Patients with Hashimoto′s thyroiditis or Graves′ disease, frequently develop antibodies against human Thyroglobulin. Thryoglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer and in Graves′ disease.

Biochem/physiol Actions

Thyroglobulin has been shown to induce expression of platelet activating factor in human peripheral blood mononuclear cells which is found elevated in some patients with thyroid disease.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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