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Key Documents

MAB8612

Sigma-Aldrich

Anti-Varicella-Zoster Virus Antibody, Glycoprotein I

Chemicon®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2b

shipped in

wet ice

Specificity

Recognizes the VZV glycoprotein I by indirect immunofluorescence, immuno-precipitation and Western blotting.

Immunogen

Epitope: Glycoprotein I
VZV HZ strain.

Application

Anti-Varicella-Zoster Virus Antibody, Glycoprotein I is an antibody against Varicella-Zoster Virus for use in IF, IP, WB, IH.
Indirect immunofluorescence: on unfixed cells shows both cytoplasmic and membrane pattern. Staining on fixed cells shows only cytoplasmic pattern.

Immunohistochemistry: reactive on formalin fixed tissue.

Western blot

Immunoprecipitation

Optimal working dilutions must be determined by the end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

1 mg/mL in 0.02M PB with 0.25M NaCl, pH 7.6, containing 0.1% sodium azide.
Format: Purified

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hirobumi Saitoh et al.
Internal medicine (Tokyo, Japan), 52(15), 1727-1730 (2013-08-02)
Disseminated visceral varicella-zoster virus (VZV) infection rarely occurs in recipients of allogeneic hematopoietic stem cell transplantation (allo-HSCT). To date, only a few cases of isolated VZV-induced fulminant hepatitis following allo-HSCT have been reported. We herein describe the case of a
Development of recombinant varicella-zoster viruses expressing luciferase fusion proteins for live in vivo imaging in human skin and dorsal root ganglia xenografts.
Stefan L Oliver, Leigh Zerboni, Marvin Sommer, Jaya Rajamani, Ann M Arvin et al.
Journal of Virological Methods null
Stefan L Oliver et al.
Journal of virology, 83(15), 7495-7506 (2009-05-29)
Glycoprotein B (gB), the most conserved protein in the family Herpesviridae, is essential for the fusion of viral and cellular membranes. Information about varicella-zoster virus (VZV) gB is limited, but homology modeling showed that the structure of VZV gB was
Shuzhao Li et al.
Cell, 169(5), 862-877 (2017-05-16)
Herpes zoster (shingles) causes significant morbidity in immune compromised hosts and older adults. Whereas a vaccine is available for prevention of shingles, its efficacy declines with age. To help to understand the mechanisms driving vaccinal responses, we constructed a multiscale
Daniel P Depledge et al.
Nature communications, 9(1), 1167-1167 (2018-03-23)
Varicella-zoster virus (VZV), an alphaherpesvirus, establishes lifelong latent infection in the neurons of >90% humans worldwide, reactivating in one-third to cause shingles, debilitating pain and stroke. How VZV maintains latency remains unclear. Here, using ultra-deep virus-enriched RNA sequencing of latently

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