O-030

Oxymorphone-3-β-D-glucuronide solution

100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₃H₂₇NO₁₀
• CAS Number: 770735-01-8
• Molecular Weight: 477.46
• MDL number: MFCD16294834
• UNSPSC Code: 41116107
• PubChem Substance ID: 329818838
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentration: 100 μg/mL in methanol: water (1:1)
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: 2-8°C
• SMILES string: CN1CC[C@]23[C@H]4Oc5c(O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(O)=O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35
• InChI: 1S/C23H27NO10/c1-24-7-6-22-13-9-2-3-11(32-21-16(28)14(26)15(27)18(34-21)20(29)30)17(13)33-19(22)10(25)4-5-23(22,31)12(24)8-9/h2-3,12,14-16,18-19,21,26-28,31H,4-8H2,1H3,(H,29,30)/t12-,14+,15+,16-,18+,19+,21-,22+,23-/m1/s1
• InChI key: ILRLBQVIWURYLX-WUDROUKASA-N

Description

General description

A certified Snap-N-Spike^® solution of Oxymorphone-3ß-D-glucuronide suitable for use in a variety of GC/MS or LC/MS applications such as pain prescription monitoring, clinical toxicology, pharmaceutical research, forensic analysis, or urine drug testing. Oxymorphone-3ß-D-glucuronide is a major metabolite of oxymorphone in urine and plasma. Oxymorphone, sold under trade names such as Opana^®, Numorphan^®, and Numorphone, is an opiate analgesic indicated for relief of moderate to severe pain.

Application

• Validation of a thin-layer chromatography/densitometry method for the characterization of invertase activity.: This study validated a TLC-densitometric method using Silica gel 60 F₂₅₄ for the characterization of invertase activity, demonstrating the technique′s robustness and reliability in analyzing enzyme activity (Ferey et al., 2016).


• Stability-Indicating TLC-Densitometric and HPLC Methods for the Simultaneous Determination of Piracetam and Vincamine in the Presence of Their Degradation Products.: This research developed and validated stability-indicating methods using TLC-densitometry with Silica gel 60 F₂₅₄ and HPLC for the simultaneous determination of piracetam and vincamine, highlighting the methods′ precision and sensitivity in the presence of degradation products (Ahmed et al., 2016).


• TLC densitometric method for the preliminary evaluation of fucoxanthin-based products.: This paper presented a TLC-densitometric method utilizing Silica gel 60 F₂₅₄ for the analysis of fucoxanthin in commercial products, showing its effectiveness for preliminary quality assessment of these products (Piovan et al., 2014).


• Modulation of the cardiac membrane-bound cyclic nucleotide phosphodiesterase: inhibition due to a contamination of TLC purified S-adenosyl-L-[methyl-3H] methionine by Zn++ ions.: This study investigated the inhibition of cardiac membrane-bound cyclic nucleotide phosphodiesterase by Zn++ ions, which were contaminants in TLC purified S-adenosyl-L-[methyl-3H] methionine using Silica gel 60 F₂₅₄, emphasizing the need for careful sample preparation in biochemical assays (Dubois et al., 1985).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Numorphan is a registered trademark of Endo Pharmaceuticals Inc.

Opana is a registered trademark of Endo Pharmaceuticals Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H226,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 75.2 °F - closed cup
• Flash Point(C): 24 °C - closed cup