T83801

Trityl chloride

97%

• Synonym(s): Chlorotriphenylmethane, Triphenylchloromethane, Triphenylmethyl chloride
• Linear Formula: (C₆H₅)₃CCl
• CAS Number: 76-83-5
• Molecular Weight: 278.78
• Beilstein: 397363
• EC Number: 200-986-4
• MDL number: MFCD00000813
• UNSPSC Code: 12352101
• PubChem Substance ID: 24900525
• NACRES: NA.22

Properties

• Assay: 97%
• bp: 230-235 °C/20 mmHg (lit.)
• mp: 109-112 °C (lit.)
• SMILES string: ClC(c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C19H15Cl/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
• InChI key: JBWKIWSBJXDJDT-UHFFFAOYSA-N

Description

Application

Protecting reagent for amines, alcohols, and thiols.

Trityl chloride can be used as a catalyst:

• In Ritter type synthesis of 1-amidoalkyl-2-naphtols through a one-pot three-component reaction of naphthol, aryl aldehydes and acetonitrile.
• In the synthesis of 1,2,4,5-tetrasubstituted imidazoles via a one-pot multi-component reaction of benzil with aldehydes, primary amines, and ammonium acetate.
• In the preparation of amido alkyl phenols via one-pot, multi-component reaction of phenols, aromatic aldehydes, and amides under solvent-free conditions.
• In one-pot, multi-component synthesis of substituted piperidines using aromatic aldehydes, amines, and β-ketoesters.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves